The Effects of Ageing

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Submitted By provbs31wm
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The Ageing Process
“How Our Bodies and Minds Change”
Aging is a process that concerns us all. The increasing armamentarium provided by molecular biology and other techniques has allowed greater understanding of some of the processes involved. Numerous definitions of aging exist; an acceptable and commonly used definition is that aging is the total of all changes an organism undergoes from its conception to its death, including development, maturation and adulthood. There are many theories about how our bodies and minds change as we age, but no matter how much research or theories have been formed, one thing remains true is that our bodies and minds does, and will, change with age and one thing can be agree upon is that the end results in all these studies is that the body and minds does go through many changes during our life time. Since the life span varies between and within species and human longevity is partially hereditary, it is clear that genetic factors, the biology of the brain, and our culture effect the function of the brain and influence the aging process ( Johnson 1993, Schacter et al. 1993, Vijg et al. 1995).
Twin studies show that genetic differences account for about a quarter of the variance in adult human lifespan. While a great deal of research has focused on diseases of aging, there are only a few informative studies on the molecular biology of the aging brain. Many molecular changes are due in part to a reduction in the size of the brain, as well as loss of brain plasticity, Recent genome-wide studies demonstrate that a relatively small number of genes exhibit age-dependent gene expression changes. Studies in rodent, monkey, and human brains estimate the number of genes exhibiting age-dependent changes to represent less than 10%, and commonly less than 5%, of the entire genome. Human studies of longevity face numerous theoretical and…...

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