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Physical Properties
Boiling point is less than 500 degrees Celsius
Melting point is between 169.0 - 170.5 degrees Celsius
Odorless and has a bitter taste
A white crystalline powder
Density is at 1.293 g/cm^3
State at room temperature= solid
Soluble in organic solvents like methanol and ethanol
Not very soluble in water and ethene

Acetaminophen (Tylenol)

Chemical Properties

IUPAC: N-(4-hydroxyphenyl)acetamide
Common Names: Paracetamol, Tylenol, Panadol, Tempera, APAP

Organic Family/ Functional Group

Biological Importance

Primary organic family: aromatics
Functional groups: alcohols (OOH) and amide (OCONHO)

Taking too much acetaminophen can lead to liver damage/failure or death
FDA recommends daily maximum of 4,000 mg for adults; overdoses of this painkiller are some of most common poisonings

Sources and Abundance
Manufactured by Ortho McNeil Pharmaceuticals Inc., G and W
Laboratories Inc., etc.
Packaged by McNeil Laboratories, CVS Pharmacy, Walgreen Co.,

Interesting Facts
Acetaminophen is the most popular pain relief medication used in the U.S. and around the world
Accounts for over 100,000 calls to poison centers,
60,000 ER visits, hundreds of deaths annually in the
In 1982, seven deaths occurred, known as Chicago
Tylenol Murders, as result of taking Extra-Strength
Tylenol caplets laced with cyanide

In 1899, Karl Morner of Germany, discovered
Acetanilide became Acetaminophen when the body metabolizes it
10 years later, German physician Joseph Friener van
Mering, first synthesized the drug Acetaminophen.
Acetaminophen was lab synthesized
First sold in 1955 as Tylenol Elixir for Children from the company McNeil Laboratories

Stable under ordinary conditions
Acetaminophen is non-corrosive and nonflammable
Doesn’t degrade significantly
When in acidic conditions, Acetaminophen can react with water producing p-aminophenol which is used for photographic solutions
Can react with cells in the liver and kidney,

Bonding and Molecular Polarity
Bond Description
7 C-H single non-polar
4 C-C single non-polar
3 C-C double non-polar
1 C-O double polar
1 C-O single polar
2 C-N single polar
1 N-H single polar
1 O-H single polar
Tylenol is a polar molecule
There are 58 electrons , 24 bonds, and 5 lone pairs in Tylenol.
20 sigma bonds and 4 pi bonds

1 carbon tetrahedral
7 carbons triangular planar
1 nitrogen triangular pyramidal
1 oxygen bent at…...

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